Lake Jocassee Waterfront Real Estate Homes For Sale. Real estate listings for sale Lake Jocassee SC on lakefront MLS by town: Salem, Pickens & more. View by price, size, acres, age, neighborhood, sq ft, bedrooms, list date & more. SC lakefront houses Upstate SC for sale. South Carolina is full of lakefront properties for sale in the upstate of Greenville / Spartanburg area to the Midlands of Columbia SC Lake Murray all the way to Lakes Moultrie & Marion in Santee. The other most popular development in the area is The Cliffs at Lake Keowee. Since there are usually very few properties for sale actually on Lake Jocassee, if you like this area, Lake Keowee real estate is much more abundant.
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